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We seek out and take in the animals who no other organization will help or would simply euthanize because they are too expensive to heal. We rescue the abandoned, beaten, bred, fought, injured, terrified, defeated and betrayed. The minute they enter our doors, we look in their eyes and promise them ALL the second chance they deserve for health, home, commitment and love, no matter the amount of time or cost involved. Our Vision is to ensure a bright future for the underdog. To end needless suffering, negligence, and abuse. To serve the City of St. Louis and surrounding metro areas and have the largest inner-city animal sanctuary in the country.

Guide Dogs for the Blind provides enhanced mobility to qualified individuals through partnership with dogs whose unique skills are developed and nurtured by dedicated volunteers and a professional staff. Established in 1942, Guide Dogs for the Blind continues its dedication to quality student training services and extensive follow-up support for graduates. Our programs are made possible through the teamwork of staff, volunteers and generous donors. Services are provided to students from the United States and Canada at no cost to them.

The mission of Operation Kindness is to care for homeless cats and dogs in a no-kill environment until each is adopted into responsible homes and to advocate humane values and behavior.

The mission of 4 Paws for Ability is to: - Enrich the lives of children with disabilities by the training and placement of quality, task trained service dogs to provide increased independence for the children and assistance to their families. - Enrich the lives of veterans from recent conflicts who have lost the use of their limbs or their hearing while in active combat. - Educate the public to accept the use of service dogs in public places. - Assist with animal rescue when possible.

To promote the humane treatment and responsible care of animals in West Michigan through education, example, placement and protection.

The Cleveland APL's mission is to foster compassion and end animal suffering. The Cleveland APL's programs primarily serve Cuyahoga county, but the organization is committed to assisting as many animals and people beyond those borders whenever our resources and capacity for care allow. The animal adoptions program is available to any person who is willing to travel to the Cleveland APL and provide a good, loving home for an animal. By law, the Cleveland APL's jurisdiction for humane law enforcement is limited to Cuyahoga county, Ohio.

The Connecticut Humane Society (CHS) is the leading resource in the state for companion animal welfare; enriching the lives of families and communities through adoption services, medical care, education, and prevention of cruelty. Four core values bring this mission to life: stewardship, quality care, community, and respect.

Mercy For Animals is dedicated to preventing cruelty to farmed animals and promoting compassionate food choices and policies.  

PAWS is a 501(c)3 non-profit organization dedicated to saving Philadelphia’s homeless, abandoned, and unwanted animals. PAWS is the city’s largest no-kill shelter and operates two high-volume, low-cost clinics serving pet owners and rescue organizations that lack access to affordable basic veterinary care. Through its adoption locations, special events, and foster care network, PAWS finds loving homes for thousands of animals each year. PAWS is working to make Philadelphia a no-kill city where every healthy and treatable pet is guaranteed a home.

Helen Woodward Animal Center is a private, non-profit organization serving San Diego County where "people help animals and animals help people." With 14 unique programs all dedicated to that mission, the Center provides lifesaving rescue and medical care to thousands of orphan pets yearly, animal assisted therapy to children and adults in need, and humane education to thousands of children, teaching them about the importance of fostering the animal-human bond.

PHS/SPCA is a private, independent, non-profit, and our scope of services goes beyond that of a so-called no-kill, or limited admission, facility. As an open-door shelter, PHS/SPCA accepts all animals brought to us, regardless of age, breed or size, and we’ve rehomed 100% of the healthy dogs and cats in our care since 2003 and promise to do this going forward. While rewarding, this isn’t our most challenging work and doesn’t define us. We accept our community’s sick, injured, abused, unwanted, stray, neglected and older animals; donations to our Hope Program enable us to help and rehome approximately 200 every month. (Sadly, private shelters in many communities never give them a chance). We rehabilitate wildlife, make spay/neuter free for our low or fixed-income residents, educate children, and investigate animal cruelty. PHS/SPCA is one of the few shelters in the entire state accredited by the American Animal Hospital association and we’re a gold-level GuideStar Exchange participant (click the seal below to access our GuideStar nonprofit report). We take our work and mission seriously, but also have fun. It's why we've adopted "Sit Happens!" as our Behavior & Training Dept slogan and have "Go Nuts” emblazoned across the back our of mobile spay/neuter clinic. Most important, we’ve earned our community’s trust, involvement and support.

Our Mission is to Rescue, Rehabilitate, and Educate until every dog has a loving and safe place to call home. We believe we can, and we will see an end to dog homelessness and abuse through legislative efforts, hard work, and strategic partnerships near and far. We will never give up, and we will never back down from the needs of all heartbeats because every life matters. Thanks to our donors, we can continue to save more lives each year - over 80,000 dogs rescued to date across Florida, Alabama, and beyond. Your contribution helps us provide critical medical care, expand our campus, create life-changing programs, and raise awareness about animal welfare. Because of you, our vision of a joyful, healing place for rescue dogs is a reality. Every wagging tail and happy adoption is a testament to your generosity. Together, we’re giving countless dogs the second chance they deserve.