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Operation Smile mobilizes a world of generous hearts to heal children's smiles and transform lives across the globe.

UNRWA USA National Committee (UNRWA USA) is an independent 501(c)(3) nonprofit organization that provides support for the humanitarian work of UNRWA though advocacy, fundraising, and education. UNRWA USA aims to educate the general American public about the situation of Palestinian refugees and generate support for UNRWA's education, health, and social service programs in all five of its geographical fields of operation.

Smile Train is an international children’s charity with a sustainable approach to a single, solvable problem: cleft lip and palate. Millions of children in developing countries with unrepaired clefts live in shame, but more importantly, have difficulty eating, breathing and speaking. Cleft repair surgery is simple, and the transformation is immediate. Our sustainable model provides training and funding to empower local doctors in 85+ developing countries to provide 100%-free cleft repair surgery in their communities. We use the “teach a man to fish” model focusing on training local doctors to perform cleft repairs in their communities. Those doctors then go on to train other doctors creating a long-term, sustainable system. Patients see their smile for the first time, parents cry tears of joy, lives and communities are changed forever. As a result of our efficiency and with the support of our donors and partners around the world, Smile Train has transformed the lives of more than one million children by giving them the power of a smile -- that's roughly 350 surgeries a day and 128,000+ every year.  

Through Health, Education, Aid and Leadership, HEAL Palestine is working to provide every young Palestinian in Gaza a chance for a brighter future.

Endangered Species International (ESI) is strongly committed to reversing the trend of human-induced species extinction, saving endangered animals, and preserving wild places! ESI uses less than 2% of its budget for management and operations. ESI won multiple Top-Rated Awards from GreatNonprofits and has reached the Platinum participation level through the GuideStar Exchange.

From crises to long term challenges, we tackle the causes and consequences of hunger. We save lives by preventing, detecting, and treating undernutrition. We enable people to provide for themselves, see their children grow up strong, and for whole communities to prosper. We constantly search for more effective solutions, while sharing our knowledge and expertise with the world.

Cultural Care Kids First Foundation, drawing on the strength of the global community of Cultural Care Au Pair, provides resources to support organizations that strive to make a lasting difference in the lives of children in need around the world.

Humanity and Inclusion is an independent and impartial international aid organization working in situations of poverty and exclusion, conflict and disaster. Working alongside persons with disabilities and other vulnerable groups, our action and testimony are focused on responding to their essential needs, improving their living conditions and promoting respect for their dignity and their fundamental rights.

Catholic Relief Services carries out the commitment of the Bishops of the United States to assist the poor and vulnerable overseas. We are motivated by the Gospel of Jesus Christ to cherish, preserve and uphold the sacredness and dignity of all human life, foster charity and justice, and embody Catholic social and moral teaching as we act to: Promote human development by responding to major emergencies, fighting disease and poverty, and nurturing peaceful and just societies; and, Serve Catholics in the United States as they live their faith in solidarity with their brothers and sisters around the world. As part of the universal mission of the Catholic Church, we work with local, national and international Catholic institutions and structures, as well as other organizations, to assist people on the basis of need, not creed, race or nationality.

The American Jewish Joint Distribution Committee (JDC) is the world's leading Jewish humanitarian organization, working in 70 countries to save Jewish lives, build Jewish life, support Israel's most vulnerable populations, and lead the Jewish community’s response to disasters and crises around the world, giving care and comfort to those most in need.

Mercy Corps exists to alleviate suffering, poverty and oppression by helping people build secure, productive and just communities.

Through core programs of disaster relief, medical care, hunger relief, and clean water, OB is dedicated to alleviating human need and suffering in the United States and around the world. Since 1978, Operation Blessing has touched the lives of millions of people in more than 90 countries and territories, including the U.S.