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Prime of life neurodegeneration is a spectrum of relatively rare diseases that often afflict people during productive, active years and lead to debilitating symptoms and early death. They are generally categorized as frontotemporal disorders and are characterized by progressive personality, behavior, language and motor decline. These diseases create a level of functional impairment that significantly compromises the ability to carry out activities of daily living. There is currently no treatment and no cure, but there is hope. Research into these diseases may be a gateway to understanding and ultimately preventing, treating and curing more common neurodegenerative diseases like Alzheimer's and Parkinson's. CurePSP is the leading organization within this disease spectrum, providing support for patients, families and caregivers; awareness and education to healthcare professionals; and global research funding. Current research into prime of life diseases, especially progressive supranuclear palsy (PSP), is showing great promise for unlocking the secrets of neurodegeneration.

Operation Smile mobilizes a world of generous hearts to heal children's smiles and transform lives across the globe.

Our mission is to facilitate, advocate and promote education, support and research for the prevention, treatment and cure of liver disease.

Mission Statement To serve our communities as an internationally-recognized pediatric and obstetric hospital that: advances family-centered care; fosters innovation; translates discoveries; educates health care providers and leaders; and advocates on behalf of children and expectant mothers.

Supporting patients and families while promoting research, education and awareness.

To optimize philanthropy in support of the mission and future of the Children's Hospital of Chicago medical center.

Shriners Hospitals for Children — Boston is a highly specialized pediatric surgical care center located in the heart of the city. It is considered one of the world’s preeminent hospitals in the treatment of children with severe burn injuries, complex skin conditions, and cleft lip and palate. Affiliated with Massachusetts General Hospital and verified by a joint program of the American Burn Association and the American College of Surgeons, Shriners Hospitals for Children — Boston meets all of the demanding standards for organizational structure, personnel qualifications, facilities resources and medical care services to ensure the best possible outcomes. All members of our staff are dedicated to providing the highest quality care in a family-centered environment.

Mental Resource Referrals, Consultation, Education

Alex’s Lemonade Stand Foundation (ALSF) is changing the lives of children with cancer by funding impactful research, raising awareness, supporting families and empowering everyone to help cure childhood cancer. When Alex, who was diagnosed with childhood cancer just before her first birthday, was 4, she told her parents she wanted to set up a front yard lemonade stand. Her plan: to give the money to doctors to help them find a cure. Her first “Alex’s Lemonade Stand,” held with the help of her older brother Patrick, raised an astonishing $2,000 in one day. While bravely fighting her own cancer, Alex continued to set up lemonade stands every year. As news spread of the remarkable girl so dedicated to helping other sick children, people everywhere were inspired to start their own lemonade stands — donating the proceeds to her cause. In 2004 when Alex passed away at the age of 8 — her stand and inspiration had raised more than $1 million towards finding a cure for the disease that took her life. Alex’s Lemonade Stand Foundation (ALSF) was started by her parents in 2005 to continue the work that Alex began. Our mission is simple: to change the lives of children with cancer through funding impactful research, raising awareness, supporting families and empowering everyone to help cure childhood cancer. Since Alex set up her first lemonade stand in 2000 — truly exemplifying the saying “When life hands you lemons, make lemonade” — we have raised more than $250 million. That money has helped to: - Fund more than 1,000 cutting-edge research projects at nearly 150 institutions. - Create a Travel For Care program to help support families of children receiving treatment and develop resources, such as our SuperSibs program to help people everywhere affected by childhood cancer. Alex’s Lemonade Stand Foundation is the living embodiment of Alex’s spirit of determination and hope. Like Alex, we believe that every person can make a difference. Together, we can bring about a cure. Please join us in “making lemons into lemonade” today!

At POGO, we give kids with cancer the support they need–not just during the difficult time around therapy, but for years after when they can face complications from the treatments that saved them. Each year in Ontario, 400 children are diagnosed with cancer and 4,000 families are currently going through active treatment or follow up care. Many of these families are accessing POGO’s financial assistance program for the unexpected costs associated with a childhood cancer diagnosis. While 82% of children survive, many survivors of brain tumours and other cancers may face learning challenges later in life. POGO counsellors work with these young people to help them match their dreams with their abilities and move on to college or university. POGO also maintains an aggressive research agenda. We are asking the types of questions that will benefit these young cancer patients, their families and survivors—in Ontario and around the world—today and well into the future.

Caring for life throughout the journey with illness and loss. We provide hospice care to hospice eligible patients. We also provide covered palliative care and bereavement care.

The mission of the Hydrocephalus Association is to promote a cure for hydrocephalus and improve the lives of those affected by the condition. This will be accomplished by collaborating with patients, caregivers, researchers, medical professionals and industry, raising awareness and funding innovative, high-impact research to prevent, treat, and ultimately, cure hydrocephalus.