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We create hope and build healthier futures. Children's Hospital Los Angeles is a nonprofit organization that depends on your generous donations to heal children in an environment that lets them thrive. Each year, more than 107,000 sick children come to the hospital for care. Support from the community helps pay for the breakthrough therapies and treatments that save young lives each year. As a leading academic children’s hospital, we fulfill our mission by: Caring for children, adolescents, young adults, families and each other, advancing knowledge, preparing future generations, and building our financial strength.

Our mission is to be a relentless force in building a world of strong, healthier lives, free of cardiovascular diseases and stroke. Our mission drives everything we do. We’re the nation’s leader in CPR education training. We help people understand the importance of healthy lifestyle choices. We provide science-based treatment guidelines to healthcare professionals to help ensure the best treatment for every patient, every time. We educate lawmakers, policy makers and the public as we advocate for changes to protect and improve the health of our communities.

City of Hope, an innovative biomedical research, treatment and educational institution, is dedicated to the prevention and cure of cancer and other life-threatening diseases, guided by a compassionate, patient-centered philosophy and supported by a national foundation of humanitarian philanthropy. City of Hope is dedicated to making a difference in the lives of people with cancer, diabetes and other serious illnesses. Our mission is to transform the future of health care by turning science into a practical benefit, hope into reality. We accomplish this by providing outstanding care, conducting innovative research and offering vital education programs focused on eliminating these diseases. Founded in 1913, City of Hope is one of only 41 comprehensive cancer centers in the nation, as designated by the National Cancer Institute. Our role as leaders in patient care, basic and clinical research, and the translation of science into tangible benefit is widely acknowledged. Our community includes research associates, scientists, doctors, nurses, allied health professionals, graduate students, fundraising specialists, marketing professionals, volunteers and an extensive support staff. We are united by our desire to find cures, save lives and transform the future of health. Every discovery we make and every new treatment we create gives people the chance to live longer, better and more fully. City of Hope continues to be a pioneer of patient centered care and remains committed to its tradition of exceptional care for patients, families and communities. Each day, we live out our credo: "There is no profit in curing the body, if, in the process, we destroy the soul."

To mobilize the resources of the entertainment industry to raise funds to provide grants to AIDS service organizations and promote awareness of HIV/AIDS issues.

The Foundation's goal is to provide the ultimate environment for a child to become their best in all areas of their life, including academic, athletic, interpersonal skills, leadership, as a mentor, and someone willing to be mentored. They hope to arm children with a variety of ways to grow intellectually, spiritually, physically, and in their relationships with themselves and others. Their program is designed to go deeper into the subjects of life, excellence, and how to pursue happiness. In the end, our long-term goal is to help them become professionals in life, to find peace of mind, so they can share this wisdom with their families, friends, and communities as leaders and examples of extraordinary living and happiness.

Established in 1985, The ALS Association is dedicated to leading the fight to treat and cure ALS through global research and nationwide advocacy while also empowering people with Lou Gehrig's Disease and their families to live fuller lives by providing them with compassionate care and support. The Association builds hope and enhances the quality of life while aggressively searching for new treatments and a cure, through global research, providing assistance for people with ALS through a nationwide network of chapters, coordinating multidisciplinary care through certified clinical care centers, and fostering government partnerships.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Race to Erase MS is dedicated to the treatment and ultimate cure of Multiple Sclerosis. Funding research is the core focus of the Foundation and all funds raised support our Center Without Walls program, a selected network of the nation's top MS research centers. This nationwide collaboration of physicians and scientists are on the cutting-edge of innovative research programs, working as a team on therapeutic approaches to eradicate MS. In addition to combating MS through research in a clinical environment, we hope to increase awareness by educating the public about this mystifying disease.

The mission of the American Diabetes Association (the Association) is to prevent and cure diabetes and to improve the lives of all people affected by diabetes. Diabetes is a disease in which the body does not produce or properly use insulin.  Insulin is a hormone that is needed to convert sugar, starches and other food into energy needed for daily life.  The cause of diabetes continues to elude the medical community, although research has shown that both genetics and environmental factors such as obesity and lack of exercise appear to play roles.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

It is the mission of Shriners Hospitals for Children to: -Provide the highest quality care to children with neuromusculoskeletal conditions, burn injuries and certain other special health care needs within a compassionate, family centered and collaborative care environment -Provide for the education of physicians and other health care professionals -Conduct research to discover new knowledge that improves the quality of care and quality of life of children and families. This mission is carried out without cost to the patient or family, and without regard to race, color, creed, sex or sect.

NAMI is the National Alliance on Mental Illness, the nation’s largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI advocates for access to services, treatment, supports and research and is steadfast in its commitment to raise awareness and build a community of hope for all of those in need. We value hope, inclusion, empowerment, compassion and fairness. NAMI envisions a world where all people affected by mental illness live healthy, fulfilling lives supported by a community that cares.