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As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Samaritan's Purse is a nondenominational evangelical Christian organization providing spiritual and physical aid to hurting people around the world. Since 1970, Samaritan's Purse has helped meet needs of people who are victims of war, poverty, natural disasters, disease, and famine with the purpose of sharing Gods love through His son, Jesus Christ. The organization serves the church worldwide to promote the Gospel of the Lord Jesus Christ.

The American Foundation for Suicide Prevention is dedicated to saving lives and bringing hope to those affected by suicide. AFSP creates a culture that’s smart about mental health through education and community programs, develops suicide prevention through research and advocacy, and provides support for those affected by suicide. AFSP has local chapters in all 50 states with programs and events nationwide.

The mission of the Alzheimer’s Foundation of America (AFA) is to provide support, services and education to individuals, families and caregivers affected by Alzheimer’s disease and related dementias nationwide, and fund research for better treatment and a cure.

The Pancreatic Cancer Action Network (PanCAN) is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer. Our mission is to take bold action to improve the lives of everyone impacted by pancreatic cancer by advancing scientific research, building community, sharing knowledge, and advocating for patients. PanCAN has invested more than $149 million in research since 2003. In the past year our nationwide PurpleStride community raised $11.8 million to fund our critical research and programs and services for patients. We have more than 700 PanCAN volunteer leaders driving local community action in our nationwide moment.

Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.

JDRF's mission is to find a cure for type 1 diabetes and its complications through the support of research. It is also committed to developing new and better treatments that improve the lives of people with type 1 diabetes in the near term and keep them healthy while we advance toward a cure. JDRF’s promise is to progressively remove the impact of T1D from the lives of those living with the disease until it is no longer a threat to them or their families. Formerly known as JDRF International or Juvenile Diabetes Research Foundation

The Palestine Children's Relief Fund (PCRF) is a non-political, non-profit organization dedicated to healing the wounds of war, occupation and poverty for children in the Middle East, regardless of their nationality, religion, race or gender.

NAMI is the National Alliance on Mental Illness, the nation’s largest grassroots mental health organization dedicated to building better lives for the millions of Americans affected by mental illness. NAMI advocates for access to services, treatment, supports and research and is steadfast in its commitment to raise awareness and build a community of hope for all of those in need. We value hope, inclusion, empowerment, compassion and fairness. NAMI envisions a world where all people affected by mental illness live healthy, fulfilling lives supported by a community that cares.

The Cystic Fibrosis Foundation's mission is to find a cure for cystic fibrosis (CF) and to improve the quality of life for people living with the disease. We accomplish this by funding life-saving research and working to provide access to quality care and effective therapies for people with CF. Our work has contributed to doubling the life expectancy for people with CF beyond the age of 18, and increasing the availability of nearly every CF drug through the Foundation's support.