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deafPLUS is a charity dedicated to enabling deaf, hard of hearing and visually impaired people to get the most out of life. We believe passionately that whatever our ability to hear or see we all have the same desire to communicate, stay safe and participate in society.

The Institute for Cancer Vaccines and Immunotherapy (previously Cancer Vaccine Institute) is the only national charity in the UK specifically funding research to fight cancer with vaccines and immunotherapy.

We connect people who care with the local causes that matter. For 35 years we've been funding and supporting the local causes doing brilliant work in Bristol, BANES, North Somerset and South Glos.Your donation will get to the grassroots groups making the difference to those most in need.

Helping families who have unmet housing needs and suffer social & economic hardship. Promoting the emotional, physical, social growth of C&YP through provision of high quality, educational & recreational activities which will enable them to flourish and develop both at home & school or college.

Winchester & District Young Carers improves the lives of children and young people with caring responsibilities by providing safe, quality support to individuals and offering an inclusive, wide ranging, and holistic approach which considers the needs of the whole family.

Jigsaw Trust aims to create more opportunities for autistic people through the provision of high quality, accessible, educational, vocational and wellbeing services through Jigsaw CABAS School, JigsawPlus adult day service and Jigsaw Enterprises including Cafe on the Park and GardenWorks.

The object of the charity is to relieve sickness and distress among children suffering from cancer and their families. The trustees do this in any way that will be beneficial to the sick child & family. This is usually in the form of free holidays taken in one of the charity's properties on the coast in Hampshire. It also provides play/medical equipment for hospitals/individuals, organises special treats, raises awareness of childhood cancer & donates funds for UK neuroblastoma research

Linc is dedicated to supporting blood cancer patients and their families across Gloucestershire. We provide both emotional and financial support and issue grants to help people who are receiving cancer care across Gloucester and Cheltenham hospitals.

Great Oaks Hospice is in Coleford in the heart of the Forest of Dean. We provide a range of services for adults with life-limiting illnesses, their families, carers and support network. All our services are free of charge and provided by experienced staff, supported by trained volunteers.

Being around horses enriches the lives of children with disabilities or learning difficulties. We offer free riding therapy that helps improve confidence, skills and self-esteem. Run entirely by volunteers we rely upon the generous donations received from our supporters to enable us to continue.

The Manchester Neurological Research Trust Fund was set up to provide support for research into neurodegenerative disorders. We are at the forefront of international research in dementia, striving to improve diagnosis and treatment. Our research work is greatly enhanced by donations.

The aim of Mosaic Clubhouse is to provide opportunities for individuals, who have been socially and vocationally disadvantaged by mental ill health, to regain the confidence and skills necessary to lead productive and satisfying lives.