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The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.

Right now, young trans people, particularly Black and Brown trans youth, are under attack across the country and around the world. The COVID-19 pandemic has exacerbated unsafe conditions for trans youth who are houseless, in foster care, in detention, and in abusive or otherwise unsafe housing situations. We want to show trans young people that they are loved, supported, and have a family of people around the world who care about them and want them to succeed. Anyone can be a Santa, join us! Transness is so beautiful and we are celebrating our magic! Deliver gifts anonymously to trans youth in need, safely.

Breast cancer is a complex disease with no simple solution. Research is the key to stopping it in its tracks. Founded in 1993 by Evelyn H. Lauder, the Breast Cancer Research Foundation (BCRF) is the largest private funder of breast cancer research in the world. We invest in the best minds in science—and foster cross-disciplinary collaboration—to examine every aspect of the disease from prevention to metastasis. Our approach accelerates the entire field and moves us closer to the answers we urgently need. We can’t stop now. Join us in fueling the world’s most promising research. With you, we will bring the end of breast cancer into focus. Learn more and get involved at BCRF.org.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Foundation's focus is increasingly on clinical and translational research, crucial to making strides toward a cure and improved therapies for those living with Parkinson's today.

Direct Relief improves the health and lives of people affected by poverty or emergency situations by mobilizing and providing essential medical resources needed for their care. Direct Relief works in all 50 U.S. states and in more than 90 countries to expand access to medicine and healthcare by equipping doctors and nurses with lifesaving medical resources.

The American Red Cross prevents and alleviates human suffering in the face of emergencies by mobilizing the power of volunteers and the generosity of donors. The American Red Cross, through its strong network of volunteers, donors and partners, is always there in times of need. We aspire to turn compassion into action so that all people affected by disaster across the country and around the world receive care, shelter and hope; our communities are ready and prepared for disasters; everyone in our country has access to safe, lifesaving blood and blood products; all members of our armed services and their families find support and comfort whenever needed; and in an emergency, there are always trained individuals nearby, ready to use their Red Cross skills to save lives. The American Red Cross' fundamental principles are: Humanity, Impartiality, Neutrality, Independence, Voluntary Service, Unity, and Universality. Our motto, "You Have the Power to Save a Life" is built upon and reflects such these values.

Memorial Sloan-Kettering Cancer Center is dedicated to leading the fight against cancer, individually focusing on each patient and creating an impact on cancer treatment and the biomedical research agenda around the world. As one of the world's premier cancer centers, Memorial Sloan Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between its physicians and scientists is one of its unique strengths, enabling it to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future.

Miry's List is a movement of neighbors and friends dedicated to welcoming new arrival refugee families into our community through inspired crowdsourcing solutions.

Our mission is to educate and empower youth and young adults in the bicycle mechanic and specialty coffee service industries. Our vision is to see kids develop agency and flourish within positive relationships, healthy lifestyles, and skill development. Our goal is to combine industry leading programs and community networks to foster the next generation of riders, young professionals, and community leaders. Our why is that many of our youth face systemic challenges in moving forward toward dreams. By creating strategic partnerships and dynamic solutions barriers in the bike world and Native Reservation can be overcome. Since 2018 Silver Stallion has established or helped establish 14 middle school mountain bike P.E. programs in the region with Outride "Riding 4 Focus." Along with that effort the Stallion started the Gallup and Navajo-Diné Composite NICA middle and high school mountain bike teams Since 2019, in partnership and with continued support from Durango Devo, Silver Stallion established DEVO/CLUB Rides program with Gallup McKinley County Schools now taking place at 4 middle schools on the Navajo Nation (Thoreau, Crownpoint, Tohatchi, Navajo). During the Pandemic Silver Stallion established “Big Blue” Mobile Ride Center truck providing Free Bike Repair events, Park Tool School Education and Free Bikes 4 Kidz distribution in remote communities throughout the Navajo Nation. Silver Stallion is partnered with Project Bike Tech establishing and supporting high school mechanic programs throughout the region.

THEIR MISSION: "The Greater Chicago Food Depository, Chicago’s food bank, believes a healthy community starts with food. We are at the center of a network of more than 700 partner organizations and programs – food pantries, soup kitchens, shelters, mobile distributions and other partners – working to bring food, dignity and hope to our neighbors across Chicago and Cook County. The Food Depository addresses the root causes of hunger with job training, advocacy and other innovative solutions. We are a proud member of Feeding America – the national network of food banks. By working to help those most in need go from hungry to hopeful, we truly become a Greater Chicago. Learn more at chicagosfoodbank.org"

To promote Talmudic ethics by providing financial assistance, scholarships and fellowships to eligible rabbis, scholars and students.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.