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Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Our mission is to channel the healing powers of the ocean to restore hope, renew purpose, and revitalize community. Operation Surf’s curriculum-based programs aim to inspire injured military and veterans to seek wellness in all aspects of their lives while providing the necessary resources, tools, and peer-to-peer support to continue this mindset indefinitely. By staying true to our core values of care, inclusion, commitment, integrity, and communication; we change participants’ lives – one wave at a time.

The Tigray Development Association is a member-based 501(c)(3) nonprofit organization established in August 1989 in Washington DC. Our primary objective is to contribute to the improvement of the livelihood of the people of Tigray through human resource development and the enhancement of health services. We address the core causes of the problems by fostering self-sufficiency at the community level, empowering Tigrayans as change agents, and developing successful collaborations with local and international communities and partners.

Millions of children are on the frontlines of conflict, their lives and futures at grave risk. Without immediate support, the world’s most vulnerable children are at risk of physical and emotional harm with devastating, lifelong consequences. That’s why Save the Children works in the hardest-to-reach places, where it’s toughest to be a child. But we need your help. Together, we can fight threats to children's lives. $50 can provide 10 warm, cozy blankets to children affected by conflict $100 helps supply a month’s worth of nutritious food to a family in crisis $200 could help provide psychosocial support to 20 children With your support, Save the Children is there before, during and after an emergency. Working together, we help communities become more resilient so that each time a crisis happens they are stronger, more likely to survive and able to recover more quickly. Your support today helps make this possible.

Founded in 1920, the American Civil Liberties Union (ACLU) is a nonprofit, multi-issue, 500,000+ member public interest organization devoted to protecting the basic civil liberties of all people in the United States. Recognized as the nation’s premier public interest law firm, the ACLU works daily in courts, legislatures, and communities to defend and preserve the freedoms guaranteed by the U.S. Constitution.  

Autism Speaks is dedicated to promoting solutions, across the spectrum and throughout the life span, for the needs of individuals with autism and their families. We do this through advocacy and support; increasing understanding and acceptance of people with autism; and advancing research into causes and better interventions for autism spectrum disorder and related conditions. ​Through partnerships and collaboration, we are committed to: ​​Increasing global understanding & acceptance of people with autism Being a catalyst for life-enhancing research breakthroughs Increasing early childhood screening & timely interventions Improving the transition to adulthood Ensuring access to reliable information & services throughout the life span.

SeaTrees protects and restores coastal ecosystems to protect ocean health and fight climate change. The organization works with communities around the world to plant and protect mangrove and kelp forests, seagrass meadows, coral reefs, and coastal watersheds. The regeneration and protection of these ecosystems provide critical habitat for countless species, sustainable long-term employment for local communities, and protect communities from storm surges and sea-level rise.

To mobilize the resources of the entertainment industry to raise funds to provide grants to AIDS service organizations and promote awareness of HIV/AIDS issues.

The mission of Planned Parenthood is to provide comprehensive reproductive and complementary health care services in settings that preserve and protect the essential privacy and rights of each individual; to advocate public policies which guarantee these rights and ensure access to such services; to provide educational programs which enhance understanding of individual and societal implications of human sexuality; to promote research and the advancement of technology in reproductive health care and encourage understanding of their inherent bioethical, behavioral, and social implications.

The Foundation's goal is to provide the ultimate environment for a child to become their best in all areas of their life, including academic, athletic, interpersonal skills, leadership, as a mentor, and someone willing to be mentored. They hope to arm children with a variety of ways to grow intellectually, spiritually, physically, and in their relationships with themselves and others. Their program is designed to go deeper into the subjects of life, excellence, and how to pursue happiness. In the end, our long-term goal is to help them become professionals in life, to find peace of mind, so they can share this wisdom with their families, friends, and communities as leaders and examples of extraordinary living and happiness.

DignityMoves works to end unsheltered homelessness in communities by building Interim Supportive Housing as a rapid, cost-effective, and, thus, scalable solution.

GlobalGiving makes it possible for anyone to give to community-led nonprofits all over the world. Our mission is to transform aid and philanthropy to accelerate community-led change. We make it possible for you to support local projects in 170 countries, giving nonprofits access to the funding, tools, and training they need to become more effective and to make our world a better place.