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The Pancreatic Cancer Action Network (PanCAN) is a nationwide network of people dedicated to working together to advance research, support patients and create hope for those affected by pancreatic cancer. Our mission is to take bold action to improve the lives of everyone impacted by pancreatic cancer by advancing scientific research, building community, sharing knowledge, and advocating for patients. PanCAN has invested more than $149 million in research since 2003. In the past year our nationwide PurpleStride community raised $11.8 million to fund our critical research and programs and services for patients. We have more than 700 PanCAN volunteer leaders driving local community action in our nationwide moment.

Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Our mission is to advance change in America by ensuring equitable access to nutritious food for all in partnership with food banks, policymakers, supporters, and the communities we serve. Through a network of more than 200 food banks, 21 statewide food bank associations, and over 60,000 partner agencies, food pantries and meal programs, we helped provide 6.6 billion meals to tens of millions of people in need last year. Feeding America also supports programs that prevent food waste and improve food security among the people we serve; brings attention to the social and systemic barriers that contribute to food insecurity in our nation; and advocates for legislation that protects people from going hungry.

The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

Founded in 1920, the American Civil Liberties Union (ACLU) is a nonprofit, multi-issue, 500,000+ member public interest organization devoted to protecting the basic civil liberties of all people in the United States. Recognized as the nation’s premier public interest law firm, the ACLU works daily in courts, legislatures, and communities to defend and preserve the freedoms guaranteed by the U.S. Constitution.  

JASMYN supports the empowerment of LGBTQIA+ teens and young adults through leadership, advocacy, resources, and a safe and affirming community.

The Stephen Siller Tunnel to Towers Foundation is to honor the sacrifice of firefighter Stephen Siller who laid down his life to save others on September 11, 2001. We also honor our military and first responders who continue to make the supreme sacrifice of life and limb for our country.

Altadena Girls is focused on restoring normalcy and a sense of self to teen girls who lost their homes in the Eaton Canyon Fire. Created by Avery Colvert, a 14-year-old living in Altadena, CA. What began as a grassroots effort to supply clothing and necessities for her classmates has grown into a national movement dedicated to giving, community, connection, resilience, and opportunity. Altadena Girls' mission is to create a safe, welcoming space where girls can heal, thrive, and build brighter futures together.

Founded in 1947, Dana-Farber Cancer Institute is committed to providing expert, compassionate care to children and adults with cancer, while advancing the understanding, treatment, cure, and prevention of cancer and related diseases. As an affiliate of Harvard Medical School and a Comprehensive Cancer Center designated by the National Cancer Institute, the Institute also provides training for new generations of physicians and scientists, designs programs that promote public health particularly among high-risk and underserved populations and disseminates innovative patient therapies and scientific discoveries in Boston, across the United States and throughout the world.

Since its founding in 1875, American Forests has pledged to be the pathfinders for creating healthy forests from coast to coast. The nonprofit organization seeks to create healthy and resilient forests, from cities to large natural landscapes, that deliver essential benefits for climate, people, water and wildlife. The organization advances its mission through forestry innovation, place-based partnerships to plant and restore forests, and movement building.

To eliminate Alzheimer's disease through the advancement of research; to provide and enhance care and support for all affected; and to reduce the risk of dementia through the promotion of brain health. The Alzheimer's Association is the world's leading voluntary health organization in Alzheimer's care, support and research. We value inclusivity, community, accountability, agility, and integrity. Our commitment to transparency, research, and diversity and inclusion helps to fulfill our vision: a world without Alzheimer's and all other dementia. In 2021, the Alzheimer's Association invested over $70 million in research, launched two new campaigns "Any Given Moment" and "More Time", and strengthened partnerships with faith-based communities. The Alzheimer's Association's powerful advocacy witnessed the Improving HOPE for Alzheimer's Act signed into law through the Association's leadership. At the beginning of the COVID-19 Pandemic, the Association's Walk to End Alzheimer's participants walked in small groups in their neighborhoods to raise $86 million.

JDRF's mission is to find a cure for type 1 diabetes and its complications through the support of research. It is also committed to developing new and better treatments that improve the lives of people with type 1 diabetes in the near term and keep them healthy while we advance toward a cure. JDRF’s promise is to progressively remove the impact of T1D from the lives of those living with the disease until it is no longer a threat to them or their families. Formerly known as JDRF International or Juvenile Diabetes Research Foundation